In clinical studies of both humans and animals, Siberian EleutheroGinseng has increased the heart rate or increased blood pressure. Both of these effects may worsen many types of heart conditions. Individuals who have heart disease, including high blood pressure and previous heart attacks, should not take eleuthero without supervision from a healthcare professional.
Even though Eleuthero appears to be safe during pregnancy and breast-feeding, some of the other plants commonly mistaken for eleuthero are known to be harmful to developing babies or small children. Eleutnero is the safest Ginseng extract.
American, Korean, Asian and Panax Ginseng should not be taken by children, during pregnancy and while breastfeeding.
Individuals with diabetes should avoid using large amounts of Ginseng because it can lower blood sugar levels, potentially resulting in hypoglycemia (blood sugar that is too low). Indications of low blood sugar include shakiness, sweating, confusion, distorted speech, and loss of muscle control. If not corrected, low blood sugar can lead to unconsciousness and even death.
What side effects should I watch for with Siberian Ginseng?
Major Side Effects
Individuals with heart disease who take Eleuthero may experience a rapid heartbeat or high blood pressure. Long-term use (more than 2 months) of Ginseng has been associated with muscle spasms due to nerve inflammation. Therefore, taking eleuthero continuously for more than 2 months is not recommended.
Less Severe Side Effects
In studies involving humans, the most commonly reported side effects from Ginseng were:
Anxiety
Breast pain
Drowsiness
Headache
What interactions should I watch for?
Prescription Drugs
Digoxin is a drug used to increase the force and to decrease the rate of heartbeats. In one reported case, an individual taking eleuthero at the same time as digoxin, developed increased blood levels of digoxin. No serious consequences resulted, but high digoxin blood levels could cause potentially dangerous changes in heart rhythm.
In laboratory studies, eleuthero has been shown to increase the time blood needs to clot. When it is taken with antiplatelet or anticoagulant drugs, the effect of the drug may be increased, resulting in uncontrolled bleeding.
Antiplatelet agents include Plavix and Ticlid
Anticoagulants include heparin and warfarin
Eleuthero may interfere with insulin and oral drugs for diabetes, such as:
When Eleuthero is taken with prescription drugs that promote sleepiness, the effects of the drug may be exaggerated, resulting in sedation or mental impairment. Prescription drugs that can cause sleepiness include:
Anticonvulsants such as carbamazepine, phenytoin and valproic acid
Barbiturates such as Phenobarbital
Benzodiazepines such as alprazolam and diazepam
Drugs for insomnia such as Ambien and Sonata
Tricyclic antidepressants such as amitriptyline, amoxapine, doxepin and nortriptyline
Because it is broken down by certain enzymes in the liver, eleuthero may possibly interfere with the use of prescription drugs that are processed by the same enzymes. Some of these drugs are:
Allergy drugs such as Allegra
Antifungal drugs such as ketoconazole (Nizoral) and Sporanox
Cancer drugs such as etoposide, paclitaxel, vinblastine, or vincristine
cyclobenzaprine (Flexeril)
Drugs for high cholesterol such as lovastatin
fluvoxamine
haloperidol (Haldol)
Oral contraceptives
theophylline (Slo-bid, Theo-Dur)
Non-prescription Drugs
Ginseng can affect the ability of blood to clot after an injury. Aspirin can also delay clotting, so eleuthero should not be taken at the same time as aspirin.
The sleep-producing effects of over-the-counter products containing diphenhydramine can be enhanced by taking eleuthero at the same time. Diphenhydramine is contained in many non-prescription sleeping pills as well as in some cough and cold products, therefore caution should be used when taking these medications with eleuthero because excessive drowsiness may result.
Herbal Products
Theoretically, if EleutheroGinseng is used with other herbs that affect blood clotting, bleeding may occur. Some of the most common herbal products that might inhibit blood clotting include:
Because EleutheroGinseng may decrease blood sugar levels, taking it with other blood sugar-lowering herbal products may result in hypoglycemia -- blood sugar that is too low. Herbals that may reduce blood sugar include:
Fenugreek
Ginger (in high amounts)
Kudzu
Panax Ginseng
Eleuthero may cause excessive sedation if taken with other sedating herbs such as:
Drinking alcohol at the same time as taking EleutheroGinseng may result in increased drowsiness.
A few individuals have reported indigestion or altered taste perception after eating spicy or bitter-tasting foods while taking eleuthero.
Some interactions between herbal products and medications can be more severe than others. The best way for you to avoid harmful interactions is to tell your doctor and/or pharmacist what medications you are currently taking, including any over-the-counter products, vitamins, and herbals.
An intoxication-like syndrome has been seen in a few newborn babies who were given Panax Ginseng or whose mothers took it while pregnant or breast-feeding. One documented case of an infant's death which was attributed to Panax ginseng intoxication has been reported. Small children and babies should not be given Panax ginseng; pregnant and breast-feeding women should also avoid taking it.
Women with hormone-dependent conditions such as endometriosis, uterine fibroids, and cancers of the breast, ovaries, or uterus should not take Panax ginseng due to its possible estrogenic effects. Men with prostate cancer should also avoid taking Panax ginseng.
In clinical studies of both humans and animals, Panax ginseng has slowed the rate and decreased the force of heartbeats. It has also reduced blood pressure in some cases. All of these effects may worsen some heart conditions. Individuals with any kind of heart disease should not take Panax ginseng without supervision from a healthcare professional.
Individuals with diabetes should avoid taking large amounts of Panax Ginseng because it can lower blood sugar levels, potentially resulting in hypoglycemia (blood sugar that is too low). Indications that blood sugar may be too low include shakiness, sweating, confusion, distorted speech, and loss of muscle control. If not corrected, low blood sugar can lead to unconsciousness and even death.
Taking Panax ginseng by mouth may cause or worsen insomnia.
Panax Ginseng side effects
Note:Most side effects from Panax ginseng have been reported in individuals who took high doses or who took Panax ginseng continually for long periods of time.
Major Side Effects
Infants given Panax ginseng may develop a condition, resembling alcohol intoxication that has lead to at least one reported death of a newborn.
Rarely, taking Panax ginseng by mouth has been associated with non-infectious hepatitis.
In other rare reports, Panax ginseng may have caused inflammation of blood vessels in the brain a condition that could result in headaches or strokes.
One case has been reported of an individual who developed anaphylaxis-like symptoms shortly after ingesting a small amount of Panax ginseng syrup. Anaphylaxis is a potentially life-threatening allergic reaction that may involve the development of a rash or hives, a sudden fall in blood pressure, swelling of the mouth and throat, or unconsciousness.
Less Severe Side Effects
Other side effects associated with taking Panax Ginseng are generally mild and temporary. They usually diminish after a few days and they may include:
Blood pressure changes
Breast pain
Diarrhea
Dizziness
Headache
Heart rate changes
Insomnia
Itching
Loss of appetite
Mood changes
Nervousness
A few individuals have experienced itchy rashes after taking or applying Panax ginseng preparations or touching Panax ginseng plants. In very rare cases, Panax ginseng may have caused a very serious skin reaction called Stevens-Johnson Syndrome. A doctor should be contacted right away if a high fever, swollen eyelids, blisters in the mouth, or red marks on the skin develop while Panax ginseng is taken.
What interactions should I watch for?
Prescription Drugs
In studies, Panax Ginseng has been shown to increase the time blood needs to clot. When it is taken with antiplatelet or anticoagulant drugs, the effect of the drug may be increased, possibly resulting in uncontrolled bleeding.
Antiplatelet agents include Plavix and Ticlid
Anticoagulants include heparin and warfarin
Some drugs used for asthma, heart problems, or other reasons can affect heart rhythm. Because Panax ginseng can change the force and rate of heart beats, it can increase the risk of side effects from drugs such as:
theophylline and related drugs for asthma
albuterol
clonidine
Viagra
Panax ginseng may interfere with insulin and oral drugs for diabetes, such as:
Panax ginseng is believed to affect levels of neurotransmitters, chemicals that carry messages from nerve cells to other cells. Antipsychotic drugs used to treat mental disorders such as schizophrenia also alter the levels of neurotransmitters. If Panax ginseng and antipsychotic drugs are taken at the same time, the effectiveness of the drug may be changed, so it is best to avoid using Panax ginseng while taking drugs such as:
Because it is broken down by certain enzymes in the liver, Panax Ginseng may possibly interfere with the use of prescription drugs that are processed by the same enzymes. Some of these drugs are:
Allergy drugs such as Allegra
Antifungal drugs such as ketoconazole (Nizoral) and Sporanox
Cancer drugs such as etoposide, paclitaxel, vinblastine, or vincristine
Drugs for high cholesterol such as lovastatin
Oral contraceptives
In reported cases, the risk of side effects such as headache, insomnia, and shakiness increased when Panax ginseng was taken with antidepressants known as MAO inhibitors. Drugs in this class include:
isocarboxazid (Marplan)
phenelzine (Nardil)
selegiline (Eldepryl)
tranylcypromine (Parnate)
Because it is a non-specific central nervous system stimulant, Panax ginseng may increase the effects and the side effects of prescription drugs that also stimulate the central nervous system. Used mainly to treat attention-deficit hyperactivity disorder, narcolepsy, and obesity; stimulant drugs can raise heart rate and blood pressure. They include:
Panax ginseng can affect the ability of blood to clot after an injury. Aspirin can also delay clotting, so Panax ginseng should not be taken orally at the same time as aspirin.
Stimulants may be included in non-prescription drugs that are used for increasing energy, losing weight, raising mental alertness, or treating colds or asthma. If Panax ginseng is taken by mouth at the same time as one of these products is being used, the central nervous system may be overstimulated, possibly resulting in insomnia, irritability, and increased blood pressure. If you are not sure whether the non-prescription drugs you take contain stimulants, ask your doctor or pharmacist before you take Panax ginseng. Herbal Products
Theoretically, if Panax ginseng is used with other herbs that affect blood clotting, bleeding may occur. Some of the most common herbal products that might inhibit blood clotting are:
Danshen
Devil's Claw
Eleuthero
Garlic
Ginger (in high amounts)
Ginkgo
Horse Chestnut
Papain
Red Clover
Saw Palmetto
If Panax Ginseng is taken at the same time as other herbs that also affect the heart, potentially dangerous changes in heart function may result. Some herbal products with heart effects are:
European Mistletoe
Ginger (in large doses)
Hawthorn
Motherwort
Pleurisy Root
Squill
Because Panax ginseng may decrease blood sugar levels, taking it with other blood sugar-lowering herbal products may result in hypoglycemia - blood sugar that is too low. Herbals that may reduce blood sugar include:
Fenugreek
Ginger (in high amounts)
Kudzu
Certain herbal products are stimulants that may result in side effects if they are taken with Panax Ginseng. These herbal products include ephedra (which has been withdrawn from the market), guarana, and mate. Taken together with Panax ginseng, any one of these herbals may cause insomnia, irritability, nervousness, and other side effects.
Foods
Caffeine increases the central nervous system stimulation effect of Panax ginseng. The combination may cause excessive nervousness and irritability, along with other signs of over-stimulation. Caffeinated beverages such as coffee, soft drinks, and tea should not be consumed when taking Panax ginseng.
Some interactions between herbal products and medications can be more severe than others. The best way for you to avoid harmful interactions is to tell your doctor and/or pharmacist what medications you are currently taking, including any over-the-counter products, vitamins, and herbals. For specific information on how Panax ginseng interacts with drugs, other herbals, and foods and the severity of those interactions, please use our Drug Interactions Checker to check for possible interactions.
American Ginseng is thought to have some estrogenic properties, which could worsen certain conditions. Women with hormone-dependent conditions such as endometriosis, uterine fibroids, and cancers of the breast, ovaries, or uterus should not take American ginseng due to its possible estrogenic effects. Men with prostate cancer should also avoid taking it.
American ginseng is thought to slow the rate and decrease the force of heart beats. It may also reduce blood pressure in some cases. All of these effects may worsen many types of heart conditions, therefore individuals with heart disease should not take American ginseng without supervision from a healthcare professional.
Taking high doses of American ginseng has been reported to worsen the symptoms of schizophrenia in some individuals.
Precautions
Individuals with diabetes should use only recommended amounts of American ginseng and monitor their blood sugar levels closely while taking it. Taking more than is recommended may result in hypoglycemia (blood sugar that is too low). Indications of low blood sugar may include shakiness, sweating, confusion, distorted speech, and loss of muscle control. If not corrected, low blood sugar can lead to unconsciousness and even death.
Very little information is available on how American ginseng might affect a developing fetus, an infant, or a small child. Therefore, its use is not recommended during pregnancy, while breast-feeding, or during early childhood.
Taking American ginseng may cause or worsen insomnia.
What side effects should I watch for?
Infrequently, the use of American ginseng has been associated with insomnia, irritability, nervousness, or restlessness, but these effects are usually mild and temporary.
Women with hormone-dependent conditions such as endometriosis, uterine fibroids, and cancers of the breast, ovaries, or uterus should not take Panax ginseng due to its possible estrogenic effects. Men with prostate cancer should also avoid taking Panax ginseng.
In clinical studies of both humans and animals, Panax ginseng has slowed the rate and decreased the force of heartbeats. It has also reduced blood pressure in some cases. All of these effects may worsen some heart conditions. Individuals with any kind of heart disease should not take Panax ginseng without supervision from a healthcare professional.
Precautions
Individuals with diabetes should avoid taking large amounts of Panax ginseng because it can lower blood sugar levels, potentially resulting in hypoglycemia (blood sugar that is too low). Indications that blood sugar may be too low include shakiness, sweating, confusion, distorted speech, and loss of muscle control. If not corrected, low blood sugar can lead to unconsciousness and even death.
Taking Panax ginseng by mouth may cause or worsen insomnia.
What side effects should I watch for with Korean Ginseng?
Note:Most side effects from Panax Ginseng have been reported in individuals who took high doses or who took Panax ginseng continually for long periods of time.
Major Side Effects
Infants given Panax ginseng may develop a condition, resembling alcohol intoxication that has lead to at least one reported death of a newborn.
Rarely, taking Panax ginseng by mouth has been associated with non-infectious hepatitis.
In other rare reports, Panax ginseng may have caused inflammation of blood vessels in the brain a condition that could result in headaches or strokes.
One case has been reported of an individual who developed anaphylaxis-like symptoms shortly after ingesting a small amount of Panax ginseng syrup. Anaphylaxis is a potentially life-threatening allergic reaction that may involve the development of a rash or hives, a sudden fall in blood pressure, swelling of the mouth and throat, or unconsciousness.
Less Severe Side Effects with Korean Ginseng
Other side effects associated with taking Panax ginseng are generally mild and temporary. They usually diminish after a few days and they may include:
Blood pressure changes
Breast pain
Diarrhea
Dizziness
Headache
Heart rate changes
Insomnia
Itching
Loss of appetite
Mood changes
Nervousness
A few individuals have experienced itchy rashes after taking or applying Panax ginseng preparations or touching Panax ginseng plants. In very rare cases, Panax ginseng may have caused a very serious skin reaction called Stevens-Johnson Syndrome. A doctor should be contacted right away if a high fever, swollen eyelids, blisters in the mouth, or red marks on the skin develop while Panax ginseng is taken.
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